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The monetary policy committee cut the overnight deposit rate to 20% from 21% and the lending rate to 21% from 22%.
A poll on Monday predicted the bank would lower its overnight interest rates by a median one percentage point, owing to eased inflation in November.
Egypt's annual urban consumer inflation edged lower to 12.3% in November, while core inflation, which strips out volatile items such as food and fuel, rose to 12.5% on an annual basis in November from 12.1%.