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The incident occurred north of Copenhagen on a railway line linking the towns of Hillerod and Kagerup, police said in a statement.
"Two local trains have collided head-on," a spokesperson for the Greater Copenhagen fire department told Reuters.
"There are injuries among the passengers. Everyone has left the trains, so no one is trapped... Large resources have been dispatched to the scene," the spokesperson added.
The number of people injured was believed to be between five and 10, according to public broadcaster DR, citing police sources.